Utumiki Wosamutsa Ukadaulo wa Ma Paclitaxel Okhazikika

Utumiki Wosamutsa Ukadaulo wamapangidwe Okhazikika a Paclitaxel Owonetsedwa

Kufotokozera Kwachidule:

Paclitaxel ndi mankhwala omwe amagwiritsidwa ntchito kwambiri polimbana ndi chotupa. Jakisoni wa paclitaxel womwe umagwiritsidwa ntchito masiku ano pachipatala umagwiritsa ntchito mafuta a polyoxyethylene castor ngati solubilizer, koma zochitika zowopsa zimakhala zambiri pakagwiritsidwe ntchito kachipatala, kotero wodwalayo ayenera kupatsidwa mankhwala odana ndi matupi awo sagwirizana, Pofuna kuthetsa mavuto obwera chifukwa cha mafuta a polyoxyethyl castor, gonjetsani zolakwika zomwe zilipo kale, ndikuwonjezera kusungunuka ndi kukhazikika kwa paclitaxel, Albumin-bound paclitaxel inayamba kukhalapo. Transfer Service for Conventional Paclitaxel Formulations.Kuti mumve zambiri, chonde onani pa intaneti.

Titumizireni imelo

Tsatanetsatane wa Zamalonda

Zolemba Zamalonda

Paclitaxel

Metabolite yachiwiri yachilengedwe yodzipatula komanso yoyeretsedwa ku khungwa, nthambi ndi masamba a gymnospermous taxus chinensis amatha kulimbikitsa kuphatikizika kwa microtubule ndikukhazikitsa ma polymerized microtubules.Maselo omwe amawonekera ku paclitaxel adziunjikira ma microtubules ambiri m'maselo.Kuchuluka kwa ma microtubuleswa kumasokoneza ntchito zosiyanasiyana za maselo, makamaka kuyimitsa magawano a cell pa siteji ya mitotic, ndikulepheretsa kugawanika kwa maselo.

Pakali pano, paclitaxel yomwe imagwiritsidwa ntchito kwambiri ndi jakisoni wa anticancer ndi zida zamankhwala (kuphatikiza ma stents ndi mabaluni).Ndi chitukuko chofulumira cha biotechnology ndi ukadaulo wazachipatala, kugwiritsa ntchito paclitaxel kumafufuzidwanso mosalekeza, ndipo mikhalidwe yosiyanasiyana ya odwala imasinthidwanso mosalekeza.Khulupirirani kuti posachedwa, kudzakhala kotetezeka komanso kothandiza kwambiri kwa madokotala ndi odwala, ndipo padzakhala mitundu yambiri ya mankhwala oletsa khansa omwe ali ndi paclitaxel omwe ali ndi mphamvu yotsutsa khansa.

Kupita patsogolo kwa polojekiti

Phunziro lachipatala latha ndipo ndondomeko yokonzekera ndi yokhwima.