Kuchita bwino ndi udindo wa paclitaxel

Paclitaxel amachokera ku Taxus chinensis ndipo ndiye chinthu choyambirira kwambiri chomwe chidapezeka kuti chimalepheretsa ma cell chotupa.Mapangidwe a paclitaxel ndi ovuta, ndipo ntchito zake zamankhwala zimawonetsedwa makamaka pochiza khansa ya m'mawere, khansa ya m'mapapo, ndi khansa ya m'mawere.Paclitaxelndi metabolite yachiwiri yotengedwa ku khungwa la Taxus chinensis ndi akatswiri a zamankhwala aku America, omwe ali ndi zotsatira zabwino zotsutsana ndi chotupa.Tiyeni tiwone momwe paclitaxel imagwirira ntchito komanso ntchito yake.

Mphamvu ndi udindo wapaclitaxel

1. Anti-chotupa zotsatira

Paclitaxel ndi anti-microtubule antitumor mankhwala.Paclitaxel ikhoza kulimbikitsa msonkhano wa microtubule mwa kulimbikitsa polymerization ya ma spinosomal tubulin subunits, ngakhale mkhalapakati wofunikira pa msonkhano wamba wa microtubule (monga GTP, guanosine triphosphate, etc.)., etc.) amathanso kukhala ndi zotsatirazi, zomwe zimapangitsa kuti pakhale ma microtubules osagwira ntchito, okhazikika.

2. Anti-cancer effect

Paclitaxel imakhala ndi zotsatira za anticancer pamizere yoyipa ya maselo a sarcoma, khansa ya m'magazi ndi khansa yapakhungu.Paclitaxel ndi mankhwala oyambanso kwa amayi omwe ali ndi khansa ya m'mawere komanso yamchiberekero.Paclitaxel imatha kumangirira ku ma microtubules, omwe amatha "kuundana" ndikuletsa kulekanitsidwa kwa ma chromosome pagawidwe lama cell, omwe amatha kupha mwachangu maselo a khansa.

3. Chithandizo cha nyamakazi

Kafukufuku wasonyeza kuti paclitaxel yavomerezedwa ndi FDA kuti azichiza nyamakazi ya nyamakazi, ndipo gel paclitaxel ndi njira yopangira mankhwala.paclitaxL zochizira nyamakazi.

Zindikirani: Kuthekera komanso kugwiritsa ntchito zomwe zafotokozedwa m'nkhaniyi zimachokera m'mabuku osindikizidwa.

Kuwerenga kowonjezereka:Yunnan Hande Biotechnology Co., Ltd. yakhala ikuyang'ana kwambiri pakupanga paclitaxel kwa zaka 28.Ndiwodzipangira yekha padziko lonse lapansi wopanga mankhwala oletsa khansa a paclitaxel omwe avomerezedwa ndi US FDA, European EDQM, Australian TGA, China CFDA, India, Japan ndi mabungwe ena olamulira dziko.bizinesi.Ngati mukufuna kugulaPaclitaxel API,chonde titumizireni pa intaneti.