Kodi paclitaxel imalimbana bwanji ndi khansa?

Paclitaxel ndi diterpenoid yotengedwa ku mtundu wa Taxus Taxus, ndipo asayansi apeza kuti ili ndi zochita zamphamvu zotsutsana ndi zotupa pakuyesa kuyesa.Pakadali pano,paclitaxelamagwiritsidwa ntchito kwambiri pochiza khansa ya m'mawere, khansa ya m'mawere, khansara ya m'mapapo yopanda maselo, khansa ya m'mapapo, khansa ya m'mimba, khansa ya m'mimba, chotupa chamutu ndi khosi, sarcoma yofewa ndi zotupa zina zoopsa, ndipo ndi imodzi mwazomwe zimachitika kawirikawiri. adagwiritsa ntchito mankhwala a chemotherapy muzochitika zachipatala.Ndiye kodi paclitaxel imalimbana bwanji ndi khansa?Tiyeni tione m'munsimu.

Kodi paclitaxel imalimbana bwanji ndi khansa?Ndizodziwika bwino kuti panthawi yogawanika kwa maselo, selo limagawidwa pawiri.chromosome ikapangidwanso, ulusi wa spindle umayikoka kuchokera pamalo ake oyamba kupita mbali zonse ziwiri, ndipo spindle imafunikira kuchotsedwa kwa ma microtubules ngati cytoskeleton kuti apange, ma Chromosome amatha kumaliza mitosis posuntha kupita kumitengo yomwe ili pansi pa nsonga ya spindle. ulusi wa spindle, kotero ma microtubules ndi ofunika kwambiri pakugawanika kwa maselo.

Mu 1979, katswiri wazamankhwala Horwitz adazindikira izipaclitaxelamatha kumangirira ku tubulin ndikulimbikitsa polymerization ya tubulin kupanga ma microtubules, potero kulepheretsa kugawanika kwa thupi kwa microtubules, kumapangitsa kuti zisapangidwe kupanga ma spindles ndi ma spindle filaments, kupanga maselo Kulephera kugawanitsa kumalepheretsa kubereka mofulumira kwa maselo a khansa ndipo kumapangitsa kuti apoptosis maselo a khansa.Chifukwa chake, pakati pa mankhwala oletsa khansa, paclitaxel imawonedwa ngati inhibitor ya microtubule mu mitosis.

Zindikirani: Kuthekera komanso kugwiritsa ntchito zomwe zafotokozedwa m'nkhaniyi zimachokera m'mabuku osindikizidwa.

Kuwerenga kowonjezereka:Yunnan Hande Biotechnology Co., Ltd. yakhala ikuyang'ana kwambiri pakupanga paclitaxel kwa zaka 28.Ndiwodzipangira yekha padziko lonse lapansi wopanga mankhwala oletsa khansa a paclitaxel omwe avomerezedwa ndi US FDA, European EDQM, Australian TGA, China CFDA, India, Japan ndi mabungwe ena olamulira dziko.bizinesi.Ngati mukufuna kugulaPaclitaxel API,chonde titumizireni pa intaneti.