Makhalidwe a Albumin-bound paclitaxel

Paclitaxel ndi mankhwala atsopano a antimicrotubule, omwe amagwiritsidwa ntchito kwambiri pochiza khansa ya ovarian, khansa ya m'mawere, khansa ya m'mapapo, zotupa zamutu ndi khosi, khansa ya m'mimba, khansa ya m'mimba ndi sarcoma yofewa. kupyolera mu kufufuza kosalekeza kwa taxanes ndi kupititsa patsogolo kosalekeza kwa teknoloji yokonzekera.Tiyeni tiwone makhalidwe a Albumin-bound paclitaxel.

Albumin-bound paclitaxel: nanoparticles opangidwa ndi paclitaxel ndi serum albumin ya anthu pogwiritsa ntchito ukadaulo wothamanga kwambiri, molekyulu imodzi ya albumin ndi mamolekyu asanu ndi awiri a paclitaxel amaphatikizidwa, komanso gawo la albumin receptor Gp60 pakhungu la cell ndi cysteine ​​​​olemera acidic secretory albumen ( SPARC) mu minofu ya chotupa imagwiritsidwa ntchito kulimbikitsa mankhwalawa kuti alowe m'maselo otupa ndikuwonjezera mphamvu ya chemotherapy.

1, Chitetezo

Albumin-bound paclitaxel: palibe cosolvent polyoxyethyl castor mafuta ofunikira, omwe amatha kuonjezera mlingo wa paclitaxel, kufupikitsa nthawi ya kulowetsedwa, ndipo palibe mankhwala omwe amafunikira.

2, Kuchiza

Albumin-bound paclitaxel safuna kupangira mankhwala kuti apewe ziwengo musanalowe.

3, Zoyipa

Albumin-womangidwa paclitaxel ndi paclitaxel liposomes: Chifukwa cha kukonza luso kukonzekera, palibe chifukwa kuwonjezera excipients monga polyoxyethyl castor mafuta, polysorbate 80, mtheradi Mowa, etc., ndipo chitetezo mankhwala wakhala bwino kwambiri.

4. Zizindikiro

Albumin-bound paclitaxel:mabuku ofunikira akuti mankhwala ake amodzi ndi kuphatikiza kwake ndi njira yochizira khansa ya m'mawere yomwe imakula mwachangu kapena kulephera pamankhwala ambiri. adachiritsidwa kale ndi paclitaxel, ndipo zotsatira zake ndizovomerezeka.

Zindikirani: Kuthekera komanso kugwiritsa ntchito zomwe zafotokozedwa m'nkhaniyi zonse zachokera m'mabuku osindikizidwa.

Yunnan Hande Biotechnology Co., Ltd yakhala ikugwira ntchito yopangapaclitaxel APIkwa zaka zoposa 20, ndipo ndi mmodzi mwa opanga okha padziko lonse lapansi a paclitaxel API, mankhwala odana ndi khansa omwe amachokera ku zomera, ovomerezedwa ndi US FDA, European EDQM, TGA yaku Australia, Chinese CFDA, India, Japan ndi mabungwe ena olamulira dziko. .Hande ikhoza kupereka osati zapamwamba zokhapaclitaxel zopangira,komanso ntchito zokweza zaukadaulo zokhudzana ndi paclitaxel formulation.Kuti mumve zambiri, chonde omasuka kulankhula nafe pa 18187887160.