Ubwino wa Albumin-bound paclitaxel

Paclitaxel ndi imodzi mwa mibadwo itatu ya mankhwala a chemotherapy, koma kusungunuka kwake m'madzi ndikochepa ndipo kumafunika kusungunuka ndi zosungunulira za organic. amangopewa hypersensitivity / kawopsedwe kawo chifukwa cha zosungunulira organic, komanso safuna pretreatment mahomoni; Ikhozanso kupanga albumin kunyamula paclitaxel kuchoka m'magazi mofulumira kwambiri, kudutsa endothelial maselo kudzera receptor mediated endocytosis, ndi kulemeretsa zambiri mu chotupa minofu. kudzera pakuthekera kwakukulu komanso kusungitsa (EPR effect) ya zotupa, zomwe zikupitilizabe kuwonetsa zabwino za pharmacokinetic.

M'nthawi ya immunotherapy, mphamvu ya mankhwala amodzi sikokwanira, ndipo chikhululukiro chamankhwala (ORR) cha mankhwala amodzi sichidutsa 20%; Njira yophatikizira mankhwala a chemotherapy ndiye malo otentha kwambiri pakuwunika kwamakono.

Potengera izi, Albumin-bound paclitaxel ili ndi zabwino zake, ORR yake ndi yapamwamba, imatha kupha maselo otupa bwino, komanso kulimbikitsa kuwonekera kwa antigen ya chotupa;Palibe mankhwala opangira mahomoni omwe amafunikira kuti apewe chitetezo chamthupi;Kuchulukitsa minofu ya chotupa kumachepetsa kuwonongeka yachibadwa minofu.

Zindikirani: Kuthekera komanso kugwiritsa ntchito zomwe zafotokozedwa m'nkhaniyi zonse zachokera m'mabuku osindikizidwa.

Yunnan Hande Biotechnology Co., Ltd yakhala ikugwira ntchito yopangapaclitaxel APIkwa zaka zoposa 20, ndipo ndi mmodzi mwa opanga okha padziko lonse lapansi a paclitaxel API, mankhwala odana ndi khansa omwe amachokera ku zomera, ovomerezedwa ndi US FDA, European EDQM, TGA yaku Australia, Chinese CFDA, India, Japan ndi mabungwe ena olamulira dziko. .Hande ikhoza kupereka osati zapamwamba zokhapaclitaxel zopangira,komanso ntchito zokweza zaukadaulo zokhudzana ndi paclitaxel formulation.Kuti mumve zambiri, chonde omasuka kulankhula nafe pa 18187887160.