Ligustrazine Ligusticum chuanxiong Tingafinye mankhwala zopangira

Zambiri Zamalonda

Ligustrazine ndi bioactive component yotengedwa ku Ligusticum chuanxiong, mankhwala achikhalidwe achi China omwe amagwiritsidwa ntchito kwambiri.Itha kulepheretsa kuphatikizika kwa mapulateleti, kukulitsa vasodilation, kukulitsa kutuluka kwa magazi muubongo komanso kukhala ndi neuroprotective effect.Jekeseni wa Ligustrazine wakhala akugwiritsidwa ntchito kwambiri pochiza matenda a ischemic, matenda a mtima, matenda a shuga a nephropathy ndi osteoarthritis wa bondo ku China.Ligustrazine yayesedwanso ngati chithandizo chachipatala cha zilonda zopanikizika, monga chithandizo cha salvage kwa odwala omwe si a Hodgkin's lymphoma, komanso ngati chithandizo cha mphumu ya bronchial ndi vertebrobasilar insufficiency.
1. Makhalidwe a Ligustrazine
Ligustrazine ndi kristalo wopanda mtundu wa acicular wokhala ndi malo osungunuka a 80-82 ° (kutsimikiza kwapang'onopang'ono) komanso kuwira kwa 190 °.Ili ndi fungo lapadera, hygroscopicity ndi sublimation yosavuta.Imasungunuka mosavuta m'madzi otentha ndi petroleum ether, chloroform ndi dilute hydrochloric acid, imasungunuka pang'ono mu ether komanso osasungunuka m'madzi ozizira.
2, Zotsatira za Ligustrazine
1. Zotsatira pamtima
2. Wonjezerani kuthamanga kwa mtima
3. Fulutsani mitsempha ya m'mitsempha yamagazi ndikuchepetsa kuthamanga kwa magazi
4. Kupititsa patsogolo kayendedwe ka ubongo
5. Imaletsa kuphatikizika kwa mapulateleti ndi antithrombotic
6. Mmene mkodzo dongosolo
7. Kupititsa patsogolo microcirculation
8. Mmene kupuma dongosolo
9. Anti chotupa
10. Kupititsa patsogolo chitetezo cha mthupi
11. Anti radiation kuvulala ndi kulimbikitsa ma radiation
3, Kupanga kwa Ligustrazine
Dimethylpyrazine inakonzedwa ndi condensation ya butanone ndi ethyl nitrite kuti apange dimethylglyoxime, yomwe inachepetsedwa ndi kuyendetsa njinga.The cyclization reaction mankhwala amasungunulidwa ndi nthunzi, ndi distillate utakhazikika, crystallized ndi zosefedwa kuti apeze zopangira za tetramethylpyrazine.Madzi recrystallization ndi activated carbon decolorization ntchito kuyenga.Pokonzekera hydrochloride yake, ethanol solution yomwe ili ndi 15% - 20% hydrogen chloride imatha kuwonjezeredwa ku acetone kupanga mchere.
4. Magawo ogwiritsira ntchito a Ligustrazine
1. Makampani opanga mankhwala: kupanga mankhwala.
2. Makampani azakudya: amagwiritsidwa ntchito ngati zokometsera, zokometsera zakumwa zoledzeretsa, zokometsera ndi zowonjezera za ndudu.

Product Parameters

MBIRI YAKAMPANI
Dzina lazogulitsa	ligustrazine
CAS	1124-11-4
Chemical Formula	C8H12N2
Brandi	Hndi
Mwopanga	YMalingaliro a kampani unnan Hande Bio-Tech Co., Ltd.
Ckunja	Kunming,Cine
Kukhazikitsidwa	1993
BMALANGIZO ASIC
Mawu ofanana ndi mawu	Tetramethylpyrazine;2,3,5,6-tetramethylpyrazine;Pyrazine, tetramethyl-;
Kapangidwe
Kulemera	136.19400
HS kodi	N / A
UbwinoStanthauzo	Mafotokozedwe a Kampani
Czotsimikizira	N / A
Kuyesa	Zosinthidwa malinga ndi zosowa za makasitomala
Maonekedwe	Mtundu wa acicular crystal
Njira Yochotsera	rhizome ya chuanxiong
Kutha Kwapachaka	Zosinthidwa malinga ndi zosowa za makasitomala
Phukusi	Zosinthidwa malinga ndi zosowa za makasitomala
Njira Yoyesera	N / A
Kayendesedwe	Zambiritransports
PayimentTerms	T/T, D/P, D/A
Oawo	Landirani kuwunika kwamakasitomala nthawi zonse;Thandizani makasitomala polembetsa zowongolera.

1.Zogulitsa zonse zomwe zimagulitsidwa ndi kampaniyo ndi zopangira zomaliza.Zogulitsazo zimayang'ana makamaka kwa opanga omwe ali ndi ziyeneretso zopanga, ndipo zopangira sizinthu zomaliza.
2.Kuthekera kothekera ndi ntchito zomwe zikuphatikizidwa m'mawu oyamba onse amachokera m'mabuku osindikizidwa.Anthu samalimbikitsa kugwiritsa ntchito mwachindunji, ndipo kugula payekha kumakanidwa.
3. Zithunzi ndi zambiri zazinthu zomwe zili patsamba lino ndizongongotchula zokhazokha, ndipo zomwe zili zenizeni ndizoyenera.