Cabazitaxel Cas 183133-96-2 Wopanga Cabazitaxil

Kufotokozera Kwachidule:

Carbataxel ndi mankhwala omwe amagwiritsidwa ntchito popanga mankhwala oletsa khansa.Carbataxel ndi ufa woyera kapena woyera womwe umakhala wosasungunuka m'madzi, koma umasungunuka mu ethanol.Njira yake yolimbana ndi khansa ndi mawonekedwe ake ndi ofanana ndi docetaxel, ndipo ali m'gulu la mankhwala odana ndi microtubule.Kudzera kuphatikiza ndi tubulin, kulimbikitsa ake kusonkhana mu microtubules, pa nthawi yomweyo zingalepheretse awa wasonkhana ndi microtubule disassembly, kuti bata microtubules, potero inhibiting selo mitosis, ndi interphase selo ntchito (interphasecellularfunctions).

Titumizireni imelo

Tsatanetsatane wa Zamalonda

Zolemba Zamalonda

Zambiri Zamalonda

Dzina:Cabazitaxel

Nambala ya CAS:183133-96-2

Chemical formula:C45H57NO14

Zofotokozera:99%

Mtundu:ufa woyera kapena woyera

Gwero:Semi-synthesized ndi 10-DAB

Mtundu:APIs

Zotsatira

Carbataxel ndi yochokera ku taxane yomwe imagwira ntchito ngati inhibitor ya microtubule, yomangiriza ku tubulin ndikulimbikitsa msonkhano wake kukhala ma microtubules, ndikuletsa kupasuka kwa ma microtubules osonkhanitsidwawa ndikukhazikitsa ma microtubules.Kulepheretsa kumeneku kumapangitsa kuti ma microtubules aphwanyidwe ndikusiya kugawanika kwa maselo, potero kuyimitsa kayendedwe ka maselo ndikuletsa kuchulukana kwa chotupa.Choncho, carbataxel imagwiritsidwa ntchito makamaka pokonzekera mankhwala oletsa khansa, imakhala ndi zotsatira zabwino zotsutsana ndi khansa, ndipo ingagwiritsidwe ntchito pochiza matenda osiyanasiyana a bakiteriya.Makamaka, carbataxel yakhala ikugwiritsidwa ntchito kwambiri pochiza prostate, bere, ovarian, mapapu, ndi khansa zina zambiri, komanso matenda a bakiteriya, kuphatikizapo sinusitis, bronchitis, chibayo, matenda a mkodzo, matenda a maso, matenda a khungu, ndi otitis media.