Zambiri Zamalonda
Artemisinin ndi mankhwala omwe amathandiza kwambiri pochiza malungo.Ndi sesquiterpene lactone yokhala ndi peroxide gulu lotengedwa ku Artemisia annua.Lili ndi makhalidwe abwino kwambiri, kuchita mofulumira, kuchotsa kutentha ndi kuthetsa kutentha kwa chilimwe, kuchepetsa kutentha kwa kusowa, kupha protozoa ndi kawopsedwe kakang'ono.Pakali pano, mphamvu ya artemisinin yochokera kuphatikiza mankhwala (ACT) zochizira malungo wafika oposa 90% padziko lonse.Zakhala zikugwiritsidwa ntchito kwambiri pochiza malungo padziko lonse lapansi.
1. Ntchito
1. Anti malungo
Malungo (omwe amadziwika kuti pendulum cold and fever disease) ndi matenda opatsirana ndi tizilombo.Ndi matenda opatsirana omwe amayamba chifukwa cha kulumidwa kwa thupi la munthu ndi Plasmodium.Zitha kuwoneka hepatosplenomegaly ndi kuchepa kwa magazi m'thupi pambuyo poukira mobwerezabwereza kwa nthawi yayitali.Artemisinin yathandizira kuchiza malungo pamlingo winawake.Mgwirizano wa peroxide m'mapangidwe a artemisinin ndi okosijeni ndipo ndi gulu lofunika kwambiri polimbana ndi malungo.Limagwirira ntchito ndikuti gulu laulere lopangidwa ndi artemisinin mu vivo limamangiriza ku mapuloteni a Plasmodium falciparum ndikusintha mawonekedwe a cell membrane a Plasmodium falciparum.Ma radicals aulere akaphatikizana ndi puloteni ya Plasmodium, nembanemba ya bilayer ya mitochondria imatupa ndikusweka, ndipo pamapeto pake imagwa, zomwe zimapangitsa kuwonongeka kwa kapangidwe ka cell ndi ntchito ya Plasmodium, ndipo chromatin yomwe ili munyukiliya idzakhudzidwanso ndi ena. kuchuluka.
2. Antitumor
Chotupa choopsa ndi chakupha choyamba kuyika thanzi la munthu pachiswe.Ngati sichimathandizidwa munthawi yake, zitha kuyika moyo pachiswe.Kuyesa kwa m'galasi kunasonyeza kuti mlingo wina wa artemisinin ukhoza kuyambitsa apoptosis yamitundu yambiri ya maselo a khansa, monga maselo a hepatoma, maselo a khansa ya m'mawere, maselo a khansa ya khomo lachiberekero ndi zina zotero, ndipo zimalepheretsa kwambiri kukula kwa maselo a khansa.Iwo anapeza kuti artemisinin akhoza kulamulira mawu a cyclin mu chotupa maselo, kumapangitsanso zotsatira za CKIs ndi kutsogolera chotupa selo mkombero kumangidwa;Kapena kuyambitsa apoptosis ndi ziletsa chotupa angiogenesis kukana zochitika ndi kukula kwa chotupa.Artemisinin ntchito pofuna kuchiza khansa ya m'magazi ndi kuchita pa selo nembanemba wa khansa ya m'magazi maselo, kuwonjezera permeability wa nembanemba ndi kusintha osmotic kuthamanga, chifukwa mu kuchuluka kwa kashiamu ndende mu maselo, kuti yambitsa calpain, kupanga selo nembanemba wake pathupi. ndi crack, imathandizira kutulutsidwa kwa zinthu za apoptotic ndikuwonjezera liwiro la apoptosis.
3. Chithandizo cha matenda oopsa a m'mapapo mwanga
Pulmonary hypertension (PAH) ndi chikhalidwe cha pathophysiological chomwe chimadziwika ndi kukonzanso kwa mitsempha ya m'mapapo ndi kukwera kwa pulmonary artery pressure mpaka malire ena.Zitha kukhala zovuta kapena syndrome.Artemisinin ntchito pofuna kuchiza m`mapapo mwanga matenda oopsa: akhoza kuchepetsa m`mapapo mwanga mtsempha wamagazi kuthamanga ndi kusintha zizindikiro odwala PAH ndi ulesi mitsempha.Zaiman et al.Anapeza kuti artemisinin ali odana ndi yotupa kwenikweni.Artemisinin ndi zinthu zake zapakati zimatha kuletsa zinthu zosiyanasiyana zotupa, komanso zimatha kuletsa kupanga nitric oxide ndi oyimira pakati otupa;Artemisinin ali immunomodulatory kwenikweni;Feng Yibai ndi ena anapeza kuti artemisinin akhoza ziletsa kuchulukana kwa mitsempha endothelial maselo ndi mitsempha yosalala minofu maselo, ndiyeno mbali yofunika kwambiri pa chithandizo cha PAH;Artemisinin akhoza ziletsa ntchito masanjidwewo metalloproteinases, potero kuletsa m`mapapo mwanga mtima kukonzanso;Artemisinin imatha kulepheretsa mafotokozedwe a ma cytokines okhudzana ndi PAH ndikuwonjezeranso mphamvu ya anti vascular remodeling ya artemisinin.
4. Kuwongolera chitetezo cha mthupi
Iwo anapeza kuti mlingo wa artemisinin ndi zotumphukira zake bwino ziletsa T lymphocyte mitogen ndi kulimbikitsa kuchuluka mbewa ndulu lymphocytes popanda cytotoxicity.Kupeza uku kuli ndi phindu lothandizira pochiza matenda a T lymphocyte mediated autoimmune.Viniga wagalasi wa Artemisia annua amatha kupititsa patsogolo chitetezo chokwanira komanso kupititsa patsogolo ntchito yonse ya seramu ya mbewa.Dihydroartemisinin akhoza mwachindunji ziletsa kuchulukana B lymphocytes, kuchepetsa katulutsidwe wa autoantibodies ndi B lymphocytes, kuchepetsa humoral chitetezo poyankha, ziletsa humoral chitetezo chokwanira ndi kuchepetsa mapangidwe chitetezo chokwanira.
5. Antifungal
Mphamvu ya antifungal ya artemisinin imapangitsanso artemisinin kuwonetsa zochita zina za antibacterial.Kafukufukuyu anatsimikizira kuti zotsalira ufa ndi madzi decoction wa artemisinin anali amphamvu antibacterial zotsatira pa anthrax, Staphylococcus epidermidis, catarrhalis ndi diphtheria, komanso anali ena antibacterial zotsatira pa chifuwa chachikulu, Pseudomonas aeruginosa, Staphylococcus aureus ndi kamwazi bacilli.
2. Munda wa ntchito
Artemisia annua amagwiritsidwa ntchito ngati mankhwala oletsa malungo.Ntchito yake yachipatala yatsimikizira kuti artemisinin ndi zotumphukira zake zimakhala ndi zotsatira zapadera pa Plasmodium falciparum ndi Plasmodium falciparum, makamaka Artemisia annua a, yomwe imakhala ndi mphamvu kuposa mankhwala ena a artemisinin pakupha ma intracellular clones a Plasmodium falciparum.
Product Parameters
| MBIRI YAKAMPANI | |
| Dzina lazogulitsa | Artemisinin |
| CAS | 63968-64-9 |
| Chemical Formula | C15H22O5 |
| Brandi | Hndi |
| Mwopanga | YMalingaliro a kampani unnan Hande Bio-Tech Co., Ltd. |
| Ckunja | Kunming,Cine |
| Kukhazikitsidwa | 1993 |
| BMALANGIZO ASIC | |
| Mawu ofanana ndi mawu | 3,12-epoxy-12h-pyranol (4,3-j) -1,2-benzodioxepin-10 (3h) -imodzi, octahydro-3,6,9-tri;artemisiaannual.,extract;huanghuahaosu;octahydro-3,6,9-trimethyl-3,12-epoxy-12h-pyrano(4,3-j) -1,2-benzodioxepin-10(;qinghausau;qinghausu; QHS; ARTEMISIN99% |
| Kapangidwe |  |
| Kulemera | 282.34 |
| HS kodi | N / A |
| UbwinoStanthauzo | Mafotokozedwe a Kampani |
| Czotsimikizira | N / A |
| Kuyesa | Zosinthidwa malinga ndi zosowa za makasitomala |
| Maonekedwe | Mtundu wa acicular crystal |
| Njira Yochotsera | Artemisia pachaka |
| Kutha Kwapachaka | Zosinthidwa malinga ndi zosowa za makasitomala |
| Phukusi | Zosinthidwa malinga ndi zosowa za makasitomala |
| Njira Yoyesera | N / A |
| Kayendesedwe | Zambiritransports |
| PayimentTerms | T/T, D/P, D/A |
| Oawo | Landirani kuwunika kwamakasitomala nthawi zonse;Thandizani makasitomala polembetsa zowongolera. |
Hande product statement
1.Zogulitsa zonse zomwe zimagulitsidwa ndi kampaniyo ndi zopangira zomaliza.Zogulitsazo zimayang'ana makamaka kwa opanga omwe ali ndi ziyeneretso zopanga, ndipo zopangira sizinthu zomaliza.
2.Kuthekera kothekera ndi ntchito zomwe zikuphatikizidwa m'mawu oyamba onse amachokera m'mabuku osindikizidwa.Anthu samalimbikitsa kugwiritsa ntchito mwachindunji, ndipo kugula payekha kumakanidwa.
3. Zithunzi ndi zambiri zazinthu zomwe zili patsamba lino ndizongongotchula zokhazokha, ndipo zomwe zili zenizeni ndizoyenera.
