Kuwongolera kwa melatonin pakugona

Kugona ndi gawo lofunikira m'moyo wamunthu watsiku ndi tsiku, lomwe limakhudza kwambiri thanzi lamunthu komanso malingaliro, momwe thupi limagwirira ntchito komanso chidziwitso.Melatonin, timadzi timene timatulutsa timadzi ta pineal, timathandiza kwambiri kuti munthu azigona mokwanira komanso kuti azigona bwino.Nkhaniyi iwunikanso momwe melatonin imayendera pakugona malinga ndi zomwe akatswiri amalemba.

Kapangidwe ndi katulutsidwe mfundo ya melatonin

Melatonin ndi mtundu wa timadzi ta indole wopangidwa ndikutulutsidwa ndi pituitary gland ya mammalian pineal gland, yomwe imakhala ndi kamvekedwe koonekeratu.Pamalo okhala ndi kuwala kokwanira, retina imamva kuwala ndikulepheretsa kaphatikizidwe ka melatonin ndi katulutsidwe kudzera mu retina-hypothalamic-pineal axis.M'malo amdima, retina sichimva kuwala, ndipo imalimbikitsa kaphatikizidwe ndi katulutsidwe ka melatonin kudzera mu retina-hypothalamic-pineal axis.

Mphamvu ya melatonin pa khalidwe la kugona

Melatoninzimalimbikitsa kugona makamaka polumikizana ndi zolandilira za melatonin kuti aziwongolera wotchi ya circadian ndikuletsa kugalamuka.Usiku, mlingo wa melatonin umakwera, zomwe zimathandiza kusintha mawotchi achilengedwe m'thupi ndikupangitsa munthu kugona.Panthawi imodzimodziyo, melatonin ingathandizenso kusunga tulo mwa kupondereza kugalamuka.Kafukufuku wasonyeza kuti kuwongolera kwa melatonin pakugona kumayenderana kwambiri ndi mlingo ndi nthawi yoperekera.

Chachitatu, kusokonezeka kwa melatonin ndi matenda okhudzana ndi kugona

Kulephera kwa melatonin kungayambitse matenda ogona komanso matenda ena okhudzana ndi kugona.Mwachitsanzo, matenda a tulo monga kusowa tulo, matenda a shift, ndi kuvutika kusinthira ku jet lag amagwirizana ndi kusokonezeka kwa melatonin secretion rhythm.Kuonjezera apo, kafukufuku wina wasonyeza kuti kupanga melatonin yosakwanira kungapangitsenso chiopsezo cha matenda a Alzheimer, kuvutika maganizo ndi matenda ena.

mapeto

Udindo wa melatonin pakuwongolera kugona waphunziridwa kwambiri pamagulu angapo.Komabe, ngakhale kuti melatonin ili ndi udindo wokhazikika pakuwongolera kugona, pali mafunso ambiri omwe akuyenera kufufuzidwanso.Mwachitsanzo, njira yeniyeni ya melatonin iyenera kuphunziridwabe;Zotsatira za melatonin pakuwongolera kugona zitha kukhala zosiyana mwa anthu osiyanasiyana (monga anthu amisinkhu yosiyana, jenda ndi zikhalidwe).Ndipo fufuzani kuyanjana pakati pa melatonin ndi zinthu zina zakuthupi ndi zamaganizo.

Kuphatikiza apo, ndikofunikira kudziwa kuti ngakhale kugwiritsa ntchito melatonin powongolera kugona kumawonetsa chiyembekezo chodalirika, chitetezo chake, mphamvu zake komanso kugwiritsa ntchito moyenera kumafunikirabe umboni wina wachipatala.Chifukwa chake, mayendedwe ofufuza amtsogolo akuyenera kuphatikiza kuyesa mayeso ochulukirapo kuti atsimikizire zotsatira zenizeni za melatonin pakuwongolera kugona ndi zovuta zina.

umboni

Bachman,JG,&Pandi-Perumal,SR(2012) .Melatonin:mankhwala ogwiritsira ntchito kupitirira matenda ogona.Journal of pineal research,52(1),1-10.

Brayne,C.,&Smythe,J.(2005)) Udindo wa melatonin mu tulo ndi kufunikira kwake kuchipatala.Journal of Pineal Research,39(3),