Paclitaxel (Paclitaxel) ndi mankhwala omwe ali ndi zovuta zowonongeka kuchokera ku zomera zachilengedwe, ndipo katundu wake wapadera wotsutsana ndi khansa amachititsa kuti azikhala ndi ntchito zosiyanasiyana pachipatala.Komabe, chifukwa chosowa komanso kuvutikira kwa m'zigawo, kupanga kwapaclitaxelzakhala zovuta.M'zaka zaposachedwa, chifukwa cha khama la akatswiri a zamankhwala a ku France, chinthu chotchedwa 10-DAB chakhala chikusiyanitsidwa bwino ndi masamba a British purple, omwe mawonekedwe ake ndi ofanana ndi paclitaxel ndipo zomwe zili pamwambazi ndi zapamwamba, zomwe zimapereka mwayi wothetsa vutoli.
Udindo wa paclitaxel
Monga mankhwala oletsa khansa, njira yayikulu ya paclitaxel ndikugwiritsa ntchito anti-chotupa poletsa kugawanika kwa maselo a chotupa.Ndi microtubule inhibitor, yomwe ingalimbikitse polymerization ya tubulin ndikuletsa depolymerization yake, motero imalepheretsa mitosis ya maselo otupa.Kuphatikiza apo, paclitaxel imathanso kuyambitsa chotupa cell apoptosis poyambitsa chitetezo chamthupi.
2. Magawo ogwiritsira ntchitopaclitaxel
1. Chithandizo cha chotupa: Paclitaxel ndiyomwe imagwiritsidwa ntchito kwambiri pochiza chotupa, makamaka zotupa zowopsa monga khansa ya m'mawere, khansa ya m'mawere ndi khansa ya m'mapapo.Itha kugwiritsidwa ntchito yokha kapena kuphatikiza ndi mankhwala ena odana ndi khansa kuti chithandizo chitheke.
2, madera ena azachipatala: Kuphatikiza pa chithandizo cha chotupa,paclitaxelamagwiritsidwanso ntchito m'magulu ena azachipatala.Mwachitsanzo, itha kugwiritsidwa ntchito popanga zodzaza mano kapena mafupa, komanso itha kugwiritsidwa ntchito pochiza matenda ena a autoimmune ndi matenda amitsempha.
Zindikirani: Mapindu omwe angakhalepo komanso momwe angagwiritsire ntchito zomwe zafotokozedwa m'nkhaniyi zimachokera m'mabuku ofalitsidwa.
Yunnan Hande Biotechnology Co., Ltd. yakhala ikuyang'ana kwambiri pakupanga paclitaxel kwa zaka 26, ndipo ndi wopanga palokha wa mankhwala odana ndi khansa a paclitaxel API ovomerezedwa ndi United States FDA, European EDQM, Australia TGA, China CFDA , India, Japan ndi mabungwe ena olamulira dziko.Yunnan Hande paclitaxel, malo ogulitsa, malonda a fakitale mwachindunji, talandiridwa kuti mufunse, 18187887160 (WhatsApp nambala yomweyo)
Nthawi yotumiza: Oct-09-2023